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Taken individually or together, the combination possibilities of CDR randomization of heavy and/or light chains requires generating a prohibitive number of bacteriophage clones to produce a clone library representing all possible combinations, the vast majority of which will be non-binding

Malemud CJ (2006) Matrix metalloproteinases (MMPs) in health and disease: an overview

Retrieved from Lacombe, V., Chabrun, F., Lacout, C., Ghali, A., Capitain, O., Patsouris, A., et al

& Somdas, M

This is especially interesting for GBM patients, since galectin-1 has been identified as a poor prognostic factor, fulfilling a key role in the aggressiveness and immune escape of GBM cells [68, 72, 102,103,104]