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10.1111/cpr.13009 18 LongoN.FrigeniM.PasqualiM

Rotator cuff injuries involve dysfunctional and/or damaged connective tissue

The homocysteine-inducible, endoplasmic reticulum (ER) stress-inducible, ubiquitin-like domain member 2 (HERPUD1) in cultured HELA cells facilitate cytoprotective effects against oxidative stress by suppressing the inositol 1,4,5-triphosphate receptor and reducing the transfer of calcium ions from the endoplasmic reticulum to mitochondria [41]