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Group II, bisphenol-A (BPA)

WB analysis Standard immunoblotting protocols were performed as previously described [29]

The treatment protocol involved two cycles of DSS administration: each cycle lasted for five days at a concentration of 2.5%, followed by a five-day interval during which the animals received only plain water

Besides, mitochondrial alterations in the functional regulation, energy metabolism and genetic stability accompany the aging process, and there has been a lot of evidence suggesting that oxidative stress and inflammation, both of which are associated with mitochondrial dysfunction, are predisposing factors of aging