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The peptide sequence, alanine-histidine-lysine bound to copper, was chosen because of how it interacts with growth factor receptors and anti-apoptotic pathways

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This was first proved by the study that immunotherapy-activated CD8 + T lymphocytes can induce ferroptosis in cancer cells by downregulating SLC7A11 and SLC3A2, encoding subunits of system X c

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