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5H, I), while overexpression of a codon-optimized L2HGDH (L2HGDH OPT ), which is resistant to the designed sgRNA, reverses this effect (Fig

[DOI] [PMC free article] [PubMed] [Google Scholar] 29.Li Y., Wei G., Chen J

As mentioned above, one advantage of medium chain fatty acids is that they are able to easily diffuse through plasma as well as mitochondrial membranes and do not require transport proteins (Schnfeld and Wojtczak, 2016)