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Vitamin D deficiency promotes epithelial barrier dysfunctionand intestinal inflammation

High-fat or high-sugar diets as trigger inflammation in the microbiota-gut-brain axis

A combination may create interactions, overlapping side effects, or risks that have not been studied

Ferrostatin-1 also has a neuroprotective impact on SH-SY5Y cells injured by rotenone and 1-methyl-4-phenylpyridinium(MPP + ) [87, 88], suggesting that ferroptosis could offer an alternative for treating PD