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Unfortunately, p53 is mutated or depleted in approximately 50% of tumors

for instance, it disupts the integrity and physiological functions of the BBB, which leads to possible undesirable aggregation of blood components, xenobiotics, and exogenous agents in the BBB by inducing CNS injury [163]

doi: 10.1007/s00213-021-05774-2 [DOI] [PubMed] [Google Scholar] 55.Charbogne P, Kieffer BL, Befort K

punctata appear to be safe, particularly in the crude extract form, its essential oil shows significant cytotoxic and hemolytic effects

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