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doi: 10.2174/13816128113190990411

These agents interact with GLP-1 receptors in brain areas involved in appetite regulation and increase feelings of fullness after meals, leading to lower voluntary food intake in adults with obesity

Regulatory and safety status: Emideltide is not approved for use in humans and is currently pending FDA review

Whether the heptapeptide fragment fully recapitulates the parent proteins effects in vivo is unresolved

Characteristic of tyrosine kinase-Iinked growth factor receptors like Met is a requisite tyrosine residue auto-phosphorylation step, which is essential for the eventual recruitment of various SH2 domain signaling proteins