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Assessment of linear correlations between variables was conducted with Pearsons correlation coefficient calculated if both variables were normally distributed and Spearmans rank coefficient if any of the compared parameters were non-normally distributed

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Multiple apoptotic pathways, including extrinsic, intrinsic, and ER stress-mediated signaling, contribute to granulosa cell apoptosis and ultimately accelerate ovarian reserve depletion (Ratts et al., 1995