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This is because alcohol acts as a direct irritant to your gastrointestinal tract - increasing the production of stomach acid, whilst also weakening the mucus layer that normally shields the stomach lining

Furthermore, the mechanical strength of the scaffolds is also essential since the matched mechanical properties with cartilage tissue could promote the chondrogenic differentiation of recruited MSCs 22,23

One of the most common causes is diabetes

A., Ismail, L