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wherein D243 is substituted with either an A, C, E, F, G, H, I, K, L, M, N, P, Q, R, S, T, V, W, or Y

While men have a higher instance of hair loss, women also suffer from thinning hair and balding conditions

This becomes critical in the presence of pathogenic variants of any type (phenotype-related, secondary, or incidental), where therapeutic options may be limited or absent

It blocks an enzyme (NNMT) that would otherwise drain a cell's NAD+, a molecule cells need for energy production

Therefore, existing treatment methods still fail to adequately meet the clinical demand for slowing disease progression and improving non-motor symptoms