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Roles of the pyruvate kinase isoform M2 in promoting cancer in manners unrelated to catalysis are reported elsewhere 132,133,134,135,136

Jumbo : Don't worry, Dave, all we want to do is kill ya

The mitochondrial SOD is most biologically important of these three

Data accumulates to bind alteration or abnormality of GPx1 expression toward the etiology of cancer, cardiovascular diseases, neurodegeneration, autoimmune disease, and diabetes