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Metallomics 9 (10), 14391446

The limiting factors include: (1) the inability of GSH to cross the cell membrane via direct absorption

PTEN: the down side of PI 3-kinase signalling

leading to a potential biochemical riboflavin deficiency worldwide ( As a matter of fact, neural tissue has a higher susceptibility to oxidative stress

40 The Nrf2/ARE pathway, by inducing antioxidant and anti-inflammatory responses, contributes significantly to the alleviation of oxidative stress and inflammation in the gut, thus playing a protective role in conditions like IBD