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[52] Despite the promising results in preclinical studies, there are still challenges that need to be addressed before translation into the clinic, including the identification of the optimal peptide targets and delivery methods, as well as the potential off-target effects and long-term safety

Bremelanotide (PT-141) has undergone more rigorous clinical investigation, though primarily in women

The shift of these specific peptides to Category 2 is a pivotal moment in regenerative medicine

However, the fact that AOXs are largely available over-the-counter with a reasonable price increases the risk that some patients can overmedicate with AOXs leading to detrimental effects

Store vials in their original boxes or wrap them in foil to block light exposure