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Kidney International 68 , 925937, doi: 10.1111/j.1523-1755.2005.00486.x (2005)

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The medications sometimes employed under standards of care include (alphabetically) Colchicine 6 , Ibuprofen, L-arginine 7 , Pentoxifylline, Potassium amino-benzoate and Tadalafil 8 and Vitamin E 9

Although small-molecule PHGDH inhibitors effectively suppress tumor proliferation in preclinical models [52, 53], their therapeutic index may be limited by the essential physiological role of de novo serine synthesis in the central nervous system [54]