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Assays were performed in 96 well plates and activity measured by monitoring the formation of DNP-GS at 340 nm ( = 9600 M- 1 cm -1 ) every 30 seconds for 10 min, in 100 mM potassium phosphate buffer (K 2 PO4) pH 6.8 at 25C [3]

Overexpression of copper-zinc superoxide dismutase in trisomy 21

T.FazioA.LipinskiS.JahnM

In the overall safety population (n = 355), the most frequently reported treatment-related adverse events were dysgeusia (41%), fatigue (28%), dizziness (26%), constipation (23%), and diarrhea (22%)