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Although the potency of a medication may not decline until after it has officially "expired," the breakdown of active ingredients occurs over time, meaning extended storage may cause a decrease in drug efficacy

Both endogenous and exogenous forms of vit-D are inactive and require two successive hydroxylation steps by cytochrome P450 (CYP) enzymes to form fully active vit-D

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"We both came here to study and then settled into our careers," Reddy said

In the human knee joint, the selenium concentration in cartilage is approximately 80 g/kg dry weight, whereas the selenium concentrations in ligament and meniscus are 270 and 307 g/kg dry weight, respectively 60,61