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In research observations, initial skin darkening has been reported within roughly three to seven days, with more noticeable pigmentation over one to two weeks

Tiny, pigmented granules indicate melanocytic origin of lesions (Table 1).3 The width of the pigmented band varies, and it can progress to total melanonychia (Figs

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Appl Environ Microbiol 67:40644069 Ray S (2015) Applications of extracellular microbial lipase: a review