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Hydrolysis is temperature-dependent and pH-dependent

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Product Name: 5-Amino-1MQ Classification: NNMT Inhibitor / Metabolic Research Compound Structural Description: Small molecule NNMT inhibitor (non-peptide), 5-amino-1-methylquinolinium CAS Number: 685079-15-6 Molecular Weight: 159.21 Da Purity: 99% (verified by HPLC and Mass Spectrometry) Physical Form: See product label for form details Intended Use: In-vitro research use only not for human consumption Related research compounds Comparable catalog records with published variants and certificate status

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In a 12-week, placebo-controlled clinical study and an open-label extension study (SUPER-1) in 277 sildenafil-treated adults with PAH (WHO Group I) [see Clinical Studies (14)] the adverse reactions that were reported by at least 10% of sildenafil-treated patients in any dosing group, and were more frequent in sildenafil-treated patients than in placebo-treated patients are shown in Table 1