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Description

Combination of dasatinib and quercetin improves cognitive abilities in aged male Wistar rats, alleviates inflammation and changes hippocampal synaptic plasticity and histone H3 methylation profile

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Sections of 4 m thickness are prepared using a paraffin microtome (HS3315, Huadu Technology, Zhejiang) and then dried in an oven (GZX-9030MBE, Boxun, Shanghai) at 60C for 1 h

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By competitively binding FOXO4, it prevents FOXO4 from sequestering p53, thereby restoring the cells intrinsic apoptotic signaling capacity

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