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Hepatocyte growth factor (HGF), a pleiotropic cytokine, plays a pivotal role in triggering various cellular activities, including the enhancement of cell proliferation, the orchestration of cellular differentiation, the promotion of cell motility, and the induction of invasive capabilities

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Week 1-4: 1mg weekly Week 5-8: 2mg weekly Week 9-12: 4mg weekly Week 13-16: 6mg weekly Week 17-20: 8mg weekly Week 21+: 12mg weekly (if tolerated) The Phase 3 TRIUMPH-4 trial used a slightly modified approach

[ CrossRef ] [ Google scholar ] [ PubMed ] Ritschka B, Storer M, Mas A, Heinzmann F, Ortells MC, Morton JP, et al

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