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72 Previous Study has shown that SAH can reduce the expression of DNA methyltransferase DNMT1 protein, lead to demethylation of the CpG islands in the NF-B gene promoter region, and increase NF-B expression, trigger the expression of pro-inflammatory senescence-associated secretory phenotype (SASP) factors, and thus induce cellular senescence in rat aortic smooth muscle cells

Differential responses to blood pressure and oxidative stress in streptozotocin-induced diabetic wistar-kyoto rats and spontaneously hypertensive rats: effects of antioxidant (honey) treatment

Tenofovir suppresses HBV replication in patients awaiting liver transplantation

Collectively, these studies provide evidence for the potential role of astrocyte senescence and dysfunction in eliciting neuroinflammation, neurotoxicity, neuronal hyperexcitability, and neurodegeneration in the aging brain

Additionally, GATA3 promotes the production of IL-4, IL-5, and IL-13 from Th2 cells [9, 10]