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34 Kwok, T

Iron metabolism in nonalcoholic fatty liver disease

10.1093/synbio/ysac011

These ligandreceptor systems are largely dependent on a transient increase in intracellular calcium concentration ([Ca 2+ ] i ), followed by the initiation of phosphorylation-dependent signaling cascades, including mitogen-activated protein kinases (MAPKs) and calcium-dependent protein kinases, that orchestrate a complex transcriptional network and the activity of immune mediators 6,7