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The rate of brain permeation indicates how fast is the process of brain drug delivery across the BBB

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In addition to fructose catabolism in the intestine, inulin supplementation also changes the fate of fructose carbons in the liver by redirecting the usage of fructose carbons to serine, glycine and GSH synthesis

The key is to recognize that anecdotal evidence and mechanistic plausibility are not substitutes for long-term safety data