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Finally, we would like to express our profound gratitude to the patients who participated in the study

BSO might deplete cysteine in vivo even though the mechanism of BSO action (i.e., inhibition of -GCS) might lead one to predict that BSO would cause a transient accumulation of cysteine (Standeven and Wetterhahn, 1991)

For instance, recent guidelines 253 on histological detection recommend classical senescence markers (high expression of p16 and p21

Cellular glutathione peroxidase knockout mice express normal levels of selenium-dependent plasma and phospholipid hydroperoxide glutathione peroxidases in various tissues