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Normal, or healthy, aging is an ill-defined term referring to the natural aging process that is devoid of significant physical or cognitive impairments and allows for the maintenance of subjective well-being (Wong, 2018)

Glucocorticoid receptor activation is involved in producing abnormal phenotypes of single-prolonged stress rats: A putative post-traumatic stress disorder model

On the other hand, inactivation of CDKN2A gene encoding the tumor suppressor p16INK4a might facilitate escape from senescence in these cells, explaining the association between p16INK4a loss and worse outcomes in PA patients ( Table 2 List of in vitro models developed for preclinical testing

Conversely, ferroptotic cells release DAMPs that activate neutrophils, amplifying inflammation (108)

Among the recent technologies in treating Parkinsons disease is nanotechnology, which has been used with the aim of delivering molecular drugs in small quantities in the brain to reduce the side effects of various drugs and medications [171]