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(Given the potential long-term consequences of NMOSD relapses, the company could not ethically include a direct placebo arm in its Phase III trial.) Ultomiris was well-tolerated overall, and most treatment-emergent events were mild or moderate in severity, according to AstraZeneca

Reading the result as a marker, not a diagnosis A high B12 indicates a cause to be identified rather than a diagnosis on its own

Baquer, Najma Z., et al

Normal Post Sclerotherapy Hyperpigmentation (Physiological Pigmentation) Post-sclerotherapy, some patients may notice hyperpigmentation occurs especially with large surface leg veins, but sometimes spider veins too

Eaton aJDG, editor: Academic Press