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investigated IGF-1 expression in a canine flexor tendon repair model at 10 days post-operation using immunohistochemical staining, revealing a significant increase in IGF-1 levels ( Although the timing of IGF-1 upregulation varies across studies, likely due to differences in species, experimental methods, and tendon locations, the consensus is that IGF-1 expression is significantly elevated during tendon healing

Neurological deficits may also improve with this treatment

the 2022 Cochrane review rates the overall antioxidant evidence as low certainty, so selenium is not a guaranteed "fertility booster" for men who already have enough

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