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Synergistic Benefits of Combined Metformin and Magnesium Supplementation Animal studies have demonstrated that combining metformin with magnesium supplementation can have synergistic effects

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An elevated Ca:Mg may also compromise synthesis of aldosterone and cortisol (Kiowski, 1992

Yan, et al

Tubulointerstitial renal fibrosis is characterized by a harmful process of progressive deposition of connective tissue in the kidney parenchyma, resulting in the deterioration of renal functions (Efstratiadis et al