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While the peptide demonstrated a favorable safety profile, its development as a prescription obesity medication was discontinued in 2007 after mixed efficacy results in larger trials

Vitamin B12 is important for proper digestion, and a deficiency can lead to digestive issues such as diarrhoea, constipation, and loss of appetite

As a water-soluble nutrient, the body possesses an efficient mechanism for its excretion: any surplus B12 is readily eliminated through urine, contributing to its remarkably low toxicity profile

The availability of nutrients in the circulation might also have a direct effect on the production of IGF-I

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