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meanwhile, upregulated fatty acid synthesis promotes the release of pro-inflammatory cytokines, continuously amplifying chronic inflammation and accelerating airway remodeling ( In COPD, the number of M2 macrophages is reduced and their FAO function is insufficient, their anti-inflammatory and tissue repair capabilities are significantly inhibited

Expression of G protein-coupled receptor kinase 4 is associated with breast cancer tumourigenesis

Phase I metabolism includes hydrolysis, oxidation, and reduction reactions which are mainly catalyzed by various drug-metabolizing enzymes (DMEs)

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