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For instance, the genetically engineered probiotic strain Escherichia coli Nissle 1917 colonizes tumor sites and continuously converts ammonia metabolites into L-arginine

The potential role of the ubiquitin-proteasome system (UPS) in the regulation of glutamine metabolism in tumor cells remains to be fully elucidated

Redox Biol (2015) 6:183

Consequently, the exact role of SHBG in neurodegenerative diseases and its clinical translational value require further validation through rigorously designed studies

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