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Description

Cells treated with MRTX1133 for indicated times (10 mM)

6 month old male APP/PS1 mice and wild-type C57 mice were used for the purpose of this study

Address correspondence to: Heng Du, Lung Cancer Center, West China Hospital, Sichuan University, No

Gomes et al., 2022)

The particle-mesh Ewald method 60 was employed to calculate long-range electrostatic interactions, whereas a smooth (10-12 ) cutoff was applied to treat van der Waals (vdW) interactions