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In the context of CNS tumors, especially glioblastoma, HTX has demonstrated in experimental models the ability to modulate relevant processes such as oxidative stress, inflammation, apoptosis and autophagy, all of which are involved in tumor progression

doi: 10.1038/bjc.2016.293 98 Van CutsemEMuroKCunninghamDBodokyGSobreroACascinuSet al

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These employ one or several TCF binding sites followed by either a fluorescent reporter or the enzyme beta-galactosidase to detect Wnt-responsive cells (DasGupta and Fuchs, 2003