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Vitamin E (800 IU daily) has some evidence supporting its use in non-diabetic adults with biopsy-proven NASH, but this is specialist-initiated, off-label use requiring discussion of potential risks, including increased risk of haemorrhagic stroke and prostate cancer with long-term use

186 Currently, insulin potentiation therapy is practiced by over 400 therapists worldwide, and the few data available indicate that it could allow a reduction of chemotherapeutic doses without compromising efficacy

438 , 439 CR disorder directly disrupts the circadian oscillation pattern of the intestinal microbiota

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Abstract Mitochondria have emerged as multifunctional organelles central to cellular metabolism, innate immunity, and cell fate determination