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GI conditions, such as chronic pancreatitis, exocrine pancreatic insufficiency, and inflammatory bowel disease, can result in a decreased ability to absorb B12 in the GI tract, leading to a deficiency despite the dog eating a balanced diet

PMID: 24867532

Prescribers should document the clinical rationale for compounding, explain to patients that the formulation is custom-prepared, and select accredited compounding pharmacies to minimize quality variability

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Their work found and described several selective NNMT inhibitors, including 5-amino-1-methylquinolinium derivatives