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A similar mechanism has been described for the prion protein PrP, wherein its mislocalization to the cytosol enables aberrant binding to cytosolic ubiquitin ligase, sequestering the enzyme and reducing its functional availabilitythereby contributing to neurodegeneration 82

Study protocol: fish oil supplement in prevention of oxaliplatin-induced peripheral neuropathy in adjuvant colorectal cancer patientsa randomized controlled trial (OxaNeuro)

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However, the regulatory paradigm experienced a massive, unprecedented political shockwave in early 2026

Thus, further research is needed to explore the correlation between a low-protein isocaloric diet and the decrease in the levels of specific amino acids in tumors