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RING Finger Protein 2 (RNF2), an E3 ubiquitin ligase, mediates monoubiquitination of histone H2A at lysine 119 (H2AK119ub), resulting in chromatin compaction and transcriptional silencing of tumor suppressor genes

Zhao H et al

People with pernicious anemia are The disorder prevents the gut from absorbing the vitamin, which means that even if a person eats foods containing vitamin B12, their body cannot use it

These injections take only a few minutes, but their benefits can last for days

5-Amino-1MQ research demonstrates the principle that targeting metabolic enzymes can modulate cellular energy status and metabolic phenotype