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Area ratios of Lys-MDA and Lys-MDMA are shown in Supplementary Fig

The principal task at this time is to determine the risk of hepatocellular injury, and this involves two considerations: the time elapsed from the toxic ingestion, and the plasma level of acetaminophen

PMID: 18094238 Di Monte DA, Chan P, Sandy MS

Conclusion: We have elucidated a new role of ERK5 in maintaining hepatocyte insulin sensitivity, via an antioxidant response involving IRS-1, PGC-1, and TRIB3, and converging on Akt activation