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Distinguished by its unique ability to inhibit the ectoenzymatic activity of CD38, Isatuximab diverges from Daratumumab by binding to a distinct epitope on CD38, which encompasses the CD38 ectoenzyme catalytic site

Amine Hassani, M

USA 110 , 1119911204 (2013)

Optogenetic inhibition reversed allodynia and pricking and cold hyperalgesia, as well as joint pain behavior, limb dysfunction and paw dexterity deficits during and after inflammation (Fig