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doi: 10.1097/QAI.0b013e3181cbdaff 124 FalutzJMamputuJCPotvinDMoyleGSoulbanGLoughreyHet al

These decreases in GSAAT content cannot be explained by reduced transcriptional activity of the corresponding GSA1 and GSA2 genes ( Figure 4G )

Betaine and liver Research from our laboratory has demonstrated that betaine exerts its protective effects through its role in the BHMT-catalyzed reaction, which not only remethylates and removes homocysteine but also eliminates its detrimental precursor, SAH (21, 29, 30, 183185)