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Signs of B12 deficiency include feeling tired, weak, and having neurological issues

Increased flux of free radicals in cells subjected to hyperthermia: detection by electron paramagnetic resonance spin trapping

Carnosine dipeptidase II (CNDP2) has been described to support the catabolism not only of cysteinylglycine 57 but also of other dipeptides, such as those containing glutamine 35

With the increasingly extensive application of deep sequencing technology, more variations will be identified in PGx, and the indexing and annotation of these variants have also enriched public database resources such as the Clinical Pharmacogenetics Implementation Consortium (CPIC), the Pharmacogenomics Knowledge Base (PharmGKB), the Dutch Pharmacogenetics Working Group (DPWG), the Pharmacogene Variation (PharmVar), the Clinical Genome Resource (ClinGen), and ClinVar (Landrum et al., 2014

It may also contribute to life-threatening arrhythmiasVT and VF