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Among different forms of liver metabolic stress dietary, alcohol, and genetic causes are briefly discussed here

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Bmj (2010) 341:c6495

These studies also addressed the role of inflammation, apoptosis and oxidative stress in progress of AFs-induced consequences, which in turn, can be considered as a scenario to characterize the susceptible signaling pathways and enzymes to develop future clinical management strategies

Additionally, narrowing eligibility criteria to specific chemotherapy protocols may yield more homogeneous cohorts for evaluating preventive interventions