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Description

In addition to the possibility of applying the c-Glue concept to new small-molecule degraders, the structural similarity to CRBN suggests that YPEL5 could be amenable to an MGD discovery strategy analogous to what has been done for IMiDs

difficile infections TCA: Taurocholate acidbile acid CSP: Competence-stimulating-peptide 5MPCA: 5-methyl-phenazine-1-carboxylic acid PYO: Pyocyanin References Jenks JD, Cornely OA, Chen SC, Thompson GR 3rd, Hoenigl M