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Although some studies have reported positive outcomes when using AOX therapy in conjunction with other fertility treatments, the evidence remains mixed, and large-scale RCTs are needed to confirm its efficacy and safety

Oxidative stress typically results from the overproduction of free radicals, such as reactive oxygen species (ROS) and reactive nitrogen species (RNS), which are generated by internal metabolic processes and external environmental factors like ultraviolet radiation, chemical pollutants, and physical overexertion [2] Studies have shown a direct correlation between excess free radicals, DNA damage, cancer cell growth, type II diabetes mellitus induction and many other deviations [3, 4]

Preconditioning by aerobic exercise reduces acute ischemic renal injury in rats

The FDA also evaluates whether benefits persist with continued use