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Res Vet Sci 61, 268-270

Thus, it is recommended to use fermented pollen which is more acceptable for nutrient absorption by the digestive tract of humans (194, 195) because microbes degrade the external pollen walls during fermentation, and its internal nutrients can easily be consumed (8)

This inhibition reduces intracellular 1-methylnicotinamide (1-MNA) production (EC50 = 2.3 M) and preserves nicotinamide availability for the NAD+ salvage pathway

It has not completed the clinical trial pathway required for regulatory approval, and there are no active Investigational New Drug (IND) applications filed with the FDA for TB-500 specifically