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Description

2019 Apr;25(2):508-536

As expected, the intra-chain salt bridge between residue 28 and the C-terminus is seen in all L-peptides, but it is formed in the DRI-peptides only for the K28E mutant

Drugs were withdrawn at 20 weeks

In brain tissue, misfolded proteins such as amyloid-beta and tau can sequester copper ions, creating local copper deficiency while simultaneously generating reactive oxygen species through aberrant metal-protein interactions