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References Sikiric P, Seiwerth S, Grabarevic Z, et al

This is not a plateau in the traditional sense , but rather the expected deceleration that occurs as body weight decreases and metabolic rate adjusts

One of the few small human studies is a 2024 investigation into the effect of BPC-157 on women with interstitial cystitis

doi: 10.3389/fphys.2012.00049

A separate analysis in Nature Medicine found that retatrutide produced significant reductions in liver fat content in participants with metabolic dysfunction-associated steatotic liver disease (MASLD), suggesting benefits beyond simple weight reduction