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The observation that replacement of the N-terminal norleucine with GABA yielded a compound with superior anti-dementia activity indicated that an N-terminal cc- amino group was not required for activity

Nevertheless, it is still needed to be elucidated whether these two oncogenic signaling pathways possess any initiating roles in the development of cancer or they are merely contributing molecules in the propagation of tumors or development of resistance to existing therapeutic agents

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For disc herniations compressing nerve roots, this neuroprotective effect may help preserve nerve function and accelerate the resolution of radiating symptoms like sciatica