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In a healthy body, mitochondria are responsible for producing adenosine triphosphate (ATP), the primary energy currency that fuels every biological process

After removal of low-quality bases and Illumina adapter sequences using Trimmomatic software (Bolger et al, 2014), sequence reads were aligned against mouse reference genome (GRCm38/mm10) using STAR software with default parameters (Dobin et al, 2013)

[10] Ribose 5-phosphate + ATP 5-Phosphoribosyl 1-pyrophosphate + AMP Additional functions In addition to producing NADPH and ribose 5-phosphate, the pentose phosphate pathway also serves other functions, both anabolic and catabolic

Pettersen H, Landheim A, Skeie I, Biong S, Brodahl M, Benson V, et al

Blood 112(11):870, 2008